Question

1. this chart shows the significance of the primary structure of amino acids. why was the one amino acid different between normal hemoglobin and sickle cell hemaglobin?

Explanation:

Sickle - cell anemia is a genetic disorder. A single - base mutation in the DNA that codes for hemoglobin leads to a change in the primary structure of the protein. This mutation causes a substitution of one amino acid (valine instead of glutamic acid) in the beta - globin chain of hemoglobin. This change in amino acid affects the shape and function of the hemoglobin molecule, causing red blood cells to sickle.

Answer:

A single - base DNA mutation led to an amino - acid substitution.