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Question
checkpoint 3: m checkpoint (during metaphase)
what the cell checks:
- are chromosomes lined up correctly?
- are spindle fibers attached properly?
- what happens if there is a problem?
- the cell will not move into anaphase
- * necesario
why is correct chromosome attachment to spindle fibers important?
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Correct chromosome attachment to spindle fibers is vital for accurate chromosome segregation during anaphase. If attachment is incorrect, chromosomes may not separate properly, leading to aneuploidy (abnormal chromosome number) in daughter cells. This can cause genetic disorders or cell death. Proper attachment ensures each daughter cell gets the correct set of chromosomes, maintaining genomic stability.
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Correct chromosome attachment to spindle fibers is important because it ensures accurate segregation of chromosomes during anaphase. This prevents aneuploidy (abnormal chromosome numbers) in daughter cells, which is crucial for maintaining genomic stability and normal cell function (or preventing genetic disorders/cell death).