Question

imagine an experiment is done to replace all of the cysteines in chain a with glycines. the structure of glycine is also shown below. how would the changes in experiment most likely impact the structure of the proinsulin protein? select all that apply. the quaternary structure in the protein would likely be altered. this change would not likely impact any levels of the proteins structure. the tertiary structure of the protein would likely be altered. the primary structure of the protein would be altered.

Explanation:

Cysteines are important for disulfide - bond formation which stabilizes tertiary and quaternary structures. Replacing them with glycines would break disulfide bonds and likely alter tertiary and quaternary structures. Since glycines are different from cysteines, the primary structure (amino - acid sequence) would also be changed. The change would have a significant impact on the protein's structure levels.

Answer:

The primary structure of the protein would be altered.
The tertiary structure of the protein would likely be altered.
The quaternary structure in the protein would likely be altered.