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Question
part a
which of these statements about enzyme inhibitors is true?
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hint 1
consider how enzymes function
a competitive inhibitor binds to the enzyme outside the active site.
the action of competitive inhibitors may be reversible or irreversible.
a non - competitive inhibitor does not change the shape of the active site.
when the product of an enzyme or a series of enzyme - catalyzed reactions acts as its inhibitor this is known as positive feedback.
- A competitive inhibitor binds to the active - site of the enzyme, not outside it, so the first option is false.
- Competitive inhibitors can bind reversibly to the active - site of an enzyme. Their action can be reversed by increasing the substrate concentration, so the second option is true.
- Non - competitive inhibitors bind to a site other than the active - site and cause a conformational change in the enzyme, including the active - site, so the third option is false.
- When the product of an enzyme or a series of enzyme - catalyzed reactions acts as its inhibitor, it is known as negative feedback, not positive feedback, so the fourth option is false.
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B. The action of competitive inhibitors may be reversible or irreversible