Question

question 45 (mandatory) (2 points) the basic defect in osteopetrosis (marble bone disease) is the activity of which cell? histiocyte osteoclast osteoblast macrophage

Explanation:

Osteopetrosis is due to defective osteoclast function. Osteoclasts are responsible for bone resorption. When their activity is impaired, excessive bone is formed, leading to the characteristic dense bones in osteopetrosis. Histiocytes are involved in immune - related functions, osteoblasts build bone but are not the primary defect in this disease, and macrophages are part of the immune system with phagocytic functions.

Answer:

B. osteoclast