Question

select the correct answer. in which enzyme would a defect majorly affect the formation of a whole new lagging strand without affecting the leading strand? a. dna ligase b. helicase c. single - strand binding protein d. topoisomerase

Explanation:

DNA ligase joins Okazaki fragments on the lagging - strand during DNA replication. A defect in it would mainly affect lagging - strand formation without impacting the leading strand as the leading strand is synthesized continuously. Helicase unwinds the DNA double - helix for both strands. Single - strand binding protein stabilizes single - stranded DNA for both strands. Topoisomerase relieves supercoiling for both strands during replication.

Answer:

A. DNA ligase