Question

a female infant is born with ambiguous genitalia due to congenital adrenogenital syndrome. deficiency of which of the following hormones is associated with the primary clinical features that will be present with this patient beginning at birth?
acth
glucocorticoids
aldosterone
testosterone

Explanation:

Congenital Adrenogenital Syndrome is mainly due to deficiency in the synthesis of glucocorticoids. The lack of glucocorticoids leads to over - production of ACTH, which in turn stimulates the adrenal cortex to produce more androgens, causing ambiguous genitalia in female infants. Aldosterone deficiency can also occur in some forms but glucocorticoid deficiency is a key feature. Testosterone is not the deficient hormone in the primary sense here. ACTH is elevated rather than deficient.

Answer:

B. Glucocorticoids