Question

a patient presents with increased trh, increased tsh, and decreased t3. which of the following condition is associated with this pattern? pituitary adenoma hashimotos graves disease cushings

Explanation:

TRH (thyrotropin - releasing hormone) stimulates TSH (thyroid - stimulating hormone) release from the pituitary. In Hashimoto's thyroiditis, the thyroid gland is attacked by the immune system, leading to decreased thyroid hormone production (low T3). The low thyroid hormone levels stimulate the hypothalamus to secrete more TRH and the pituitary to secrete more TSH in an attempt to increase thyroid hormone production. In pituitary adenoma, TSH - secreting adenomas would cause high TSH but not necessarily the pattern of high TRH and low T3. Graves' disease is a hyperthyroid condition with high thyroid hormones, not low T3. Cushing's is related to cortisol excess and not directly to this thyroid - hormone related pattern.

Answer:

B. Hashimoto's