Question

what is the abnormal finding associated with multiple myeloma and plasmacytoma on serum protein electrophoresis? please select your answer... a bence jones proteinuria b reversed a:g ratio c hypercalcemia d m - spike

Explanation:

• Bence Jones proteinuria is detected in urine, not serum protein electrophoresis.
• Reversed A:G ratio can occur in multiple conditions but is not the specific abnormal finding for these two malignancies on serum electrophoresis.
• Hypercalcemia is a metabolic abnormality, not an electrophoresis finding.
• M-spike (monoclonal spike) is a distinct peak seen on serum protein electrophoresis, caused by the excessive monoclonal immunoglobulins produced by the abnormal plasma cells in both multiple myeloma and plasmacytoma.

Answer:

D. M-spike